老太熟妇性bbwbbwbbw,男女xxoo娇喘呻吟在线观看,呻吟 玩弄 翻搅 花蒂 肿大,99热最新成人国产精品

熱門搜索: 硫酸角質(zhì)素(KS)ELISA試劑盒(種屬:魚) 白介素6(IL6)ELISA試劑盒(種屬:魚) 魚白介素10(IL10)ELISA試劑盒發(fā)貨及時 斑馬魚白介素12BELISA試劑盒發(fā)貨及時 兔載脂蛋白B(apo-B)ELISA試劑盒發(fā)貨及時 兔孕酮(PROG)ELISA試劑盒發(fā)貨及時 兔羥脯氨酸(Hyp)ELISA試劑盒發(fā)貨及時 兔抗酒石酸酸性磷酸酶ELISA試劑盒發(fā)貨及時 兔晶體蛋白α(Cryα)ELISA試劑盒發(fā)貨及時 兔結(jié)締組織生長因子ELISA試劑盒發(fā)貨及時 兔基質(zhì)金屬蛋白酶9ELISA試劑盒發(fā)貨及時 兔肺表面活性物質(zhì)相ELISA試劑盒發(fā)貨及時 CD206分子ELISA試劑盒(種屬:小鼠) CC趨化因子受體6ELISA試劑盒(種屬:小鼠) 阻抑素(PHB)ELISA試劑盒(種屬:大鼠) 中性內(nèi)肽酶;腦啡ELISA試劑盒(種屬:大鼠)

技術(shù)文章/ Technical Articles

您的位置:首頁  /  技術(shù)文章  /  引用大鼠ELISA科研檢測試劑盒的文獻(xiàn)

引用大鼠ELISA科研檢測試劑盒的文獻(xiàn)

更新時間:2023-09-19      瀏覽次數(shù):1374

引用大鼠ELISA科研檢測試劑盒的文獻(xiàn)


文獻(xiàn)收集:

Epimedium Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3- Mediated Pyroptosis

引用試劑盒:

種屬:大鼠

IL-1β (RJ15465), IL-18 (RJ15463),TNF-α (RJ16622), IL-6 (RJ15478), IL-10 (RJ15453),iNOS(RJ16565) , MDA (RJ15503), ROS(RJ15780) ,CAT(RJ15737),SOD(RJ16691) ,GSHPx(RJ25745) , LDH (RJ16172)

 

638272614877654132225.jpg

IF:7.675


Abstract: Cerebral ischemia/reperfusion causes exacerbated neuronal damage involving excessive neuroinflammation and oxidative stress. ROS is considered a signal molecule to activate NLRP3; thus, the ROS/NLRP3/pyroptosis axis plays a vital role in the pathogenesis of cerebral ischemia/reperfusion injury (CIRI). Therefore, targeting the inhibition of the ROS/NLRP3/pyroptosis axis may be a promising therapeutic tactic for CIRI. Epimedium (EP) contains many active ingredients (ICA, ICS II, and ICT), which have a wide range of pharmacological activities. However, whether EP can protect against CIRI remains unknown. Thus, in this study, we designed to investigate the effect and possible underlying mechanism of EP on CIRI. The results showed that treatment with EP dramatically mitigated brain damage in rats following CIRI, which was achieved by suppressing mitochondrial oxidative stress and neuroinflammation. Furthermore, we identified the ROS/NLRP3/pyroptosis axis as a vital process and NLRP3 as a vital target in EP-mediated protection. Most interestingly, the main compounds of EP directly bonded with NLRP3, as reflected by molecular docking, which indicated that NLRP3 might be a promising therapeutic target for EP-elicited cerebral protection. In conclusion, our findings illustrate that ICS II protects against neuron loss and neuroinflammation after CIRI by inhibiting ROS/NLRP3-mediated pyroptosis.


image.png









微信掃一掃

郵箱:2450868877@qq.com

傳真:86-區(qū)號-傳真號碼

地址:上海市楊浦區(qū)鐵嶺路32號1519-10室

Copyright © 2025 上海仁捷生物科技有限公司版權(quán)所有   備案號:滬ICP備16052159號-1   總訪問量:317677   技術(shù)支持:化工儀器網(wǎng)

TEL:17302193538

掃碼加微信
国产边打电话边做对白在线| 当着全班面被c到高潮哭视频| 啊灬用力灬啊灬啊灬啊灬a片男男| 大肉大捧一进一出| 国产小呦泬泬99精品| 母亲とが话しています播放| 太长又太大又太粗太疼了| 国产寡妇xxxx猛交69| 92久久偷偷做嫩草影院免费看| 极品新婚夜少妇真紧| 裙底下的男友1v1校园高h| 翁与小莹最新第九部| 扒开粉嫩细缝喷白浆sex| 久久精品国产一区二区三区| 最近免费中文字幕2018视频| 亚洲欧美自偷自拍另类小说| 国产在线av一区二区麻豆董小宛| 国产精品亚洲专区无码牛牛| 亚洲精品成人区在线观看| 少妇高潮一区二区三区99| gogogo高清在线观看视频| 男男啪啪激烈高潮cc漫画免费| 免费av网站| 中文字幕爆乳巨爆乳系列| 啊┅┅快┅┅用力啊岳| 无码人妻精品一区二区三区在线| 国产人妻人伦精品无码.麻豆| 中文字幕人成乱码熟女香港| 51国产偷自视频区视频| 熟妇内谢69xxxxxa片| 久久久久99人妻一区二区三区| 人妻激情偷乱一区二区三区| 无码人妻一区二区三区精品视频| 极品尤物一区二区三区| WWW色情成人免费视频软件| 少妇性按摩无码中文a片| 亚洲熟女av中文字幕男人总站| 国产天美传媒一起又看流星雨| 色情无码www视频无码区小黄鸭| 两个人看的www视频免费完整版| 欧美+国产+日产|